Sharks interim coach JP Pietersen will have to dig deep into his loose forward stocks or be innovative after several key players were injured on Saturday.
The Bulls earned a second consecutive comeback victory against Edinburgh on Friday, earning the praise of their coach Johan Ackermann.
Springbok scrumming machine Frans Malherbe, who's been out of action since April 2025, has suffered another setback in his recovery.
The Sharks produced a statement performance to defeat the Stormers 30-19 in a United Rugby Championship clash at a sold-out Cape Town Stadium, ending the hosts' perfect start to the season.
The Lions were forced to settle for a second consecutive draw in difficult conditions as they shared the spoils 24-24 with the Ospreys in a United Rugby Championship clash on Friday night.
The Vodacom Bulls dug deep to claim a dramatic 19-17 win over Edinburgh on Friday night, sealing their first-ever United Rugby Championship victory in the Scottish capital after a tense comeback.