Wales head coach Steve Tandy has adjusted his starting XV for Friday's Six Nations meeting with Ireland at the Aviva Stadium, including recalls and injury-forced reshuffles.
England head coach Steve Borthwick has made no less than nine changes to his matchday 23 that will face Italy in the Six Nations at the Stadio Olimpico in Rome on Saturday.
The original Six Nations trophy has been severely damaged in an accident, resulting in the organisers rolling out a new trophy for the 2027 edition.
Ireland are awaiting further assessments on star winger James Lowe, who is recovering from a groin injury sustained during their recent win over England.
England's Six Nations title hopes were effectively ended after a record 42-21 defeat to Ireland at Allianz Stadium, Twickenham, with Ellis Genge apologising to supporters and admitting the squad had "believed the hype" after their opening-round win.
England head coach Steve Borthwick says he will have a long, hard look at how he sets up his team after they suffered a second consecutive defeat in the Six Nations.