Back-rower Gregory Alldritt has been handed the French captaincy in the absence of superstar Antoine Dupont, while Maxime Lucu starts scrumhalf as France face Scotland.
Celebrated scrumhalf Antoine Dupont revealed he is set for a long stint on the sidelines after tearing cruciate ligaments in his knee.
England scored seven tries to see off Italy 47-24 in a one-sided Six Nations encounter at Twickenham on Sunday.
Wales were made to count the cost of a disastrous first 60 minutes after Scotland claimed a 35-29 victory in the Six Nations on Saturday.
France produced a stunning display at the Aviva Stadium to thrash Ireland 42-27 in their Six Nations clash on Saturday.
Springbok head coach Rassie Erasmus has proposed a major change to the international rugby calendar to ease the player workload for South Africa's top internationals.