Real Madrid's Champions League opener under Xabi Alonso turned into a test of resilience as Trent Alexander-Arnold lasted only five minutes before suffering a hamstring injury.
England captain Harry Kane scored twice as Bayern Munich capitalised on a series of defensive errors to beat Chelsea 3-1 in their Champions League opener.
Chelsea manager Enzo Maresca is bracing for a formidable start to the club's Champions League campaign, with a high-profile clash against Bayern Munich.
Two penalties from Kylian Mbappe helped ten-man Real Madrid to overcome Marseille 2-1 in the opening Champions League clash at the Santiago Bernabeu on Tuesday.
Barcelona will be without teenage sensation Lamine Yamal for their Champions League opener against Newcastle United on Thursday, with the winger sidelined by a groin injury.
North London rivals Tottenham and Arsenal both kicked off their respective Champions League campaigns with wins on Tuesday night, although in very different styles.