Tottenham were left sweating over Micky van de Ven's fitness after the defender missed training on Tuesday, just a day before their crucial Champions League clash with Eintracht Frankfurt.
Hansi Flick has praised Barcelona's resilience after a demanding 4-2 Champions League win away to Slavia Praha on Wednesday, but admitted his satisfaction was tempered by concern over Pedri's injury.
Eddie Howe has praised Newcastle United's performance but admitted concern over Bruno Guimaraes after the captain was forced off during a convincing 3-0 Champions League win over PSV Eindhoven.
Chelsea are continuing to grapple with a virus that has disrupted preparations ahead of their upcoming Champions League fixture, with Enzo Fernandez the latest to be affected.
Tottenham Hotspur defeated ten-man Borussia Dortmund 2-0 in their UEFA Champions League encounter at the Tottenham Hotspur Stadium on Wednesday evening.
Champions League holders Paris Saint-Germain suffered a 2-1 defeat away to Portuguese side Sporting on Tuesday.