Arsenal will be without William Saliba and Gabriel Martinelli for Wednesday's Carabao Cup fourth-round clash against Brighton as Mikel Arteta's injury concerns continue to grow.
Bayer Leverkusen have suffered a major blow to their Bundesliga title aspirations after confirming that Ezequiel Fernandez will be sidelined for up to eight weeks with a knee ligament injury.
Real Madrid captain Dani Carvajal has suffered another major injury setback and will be sidelined for up to three months after being diagnosed with a knee problem that requires surgery.
Barcelona have been handed a major boost after Robert Lewandowski returned to full training ahead of their La Liga match against Elche this upcoming Sunday.
Scott McTominay has returned to full training with Napoli ahead of their Champions League trip to PSV Eindhoven, but Rasmus Hojlund will remain sidelined through injury.
Barcelona's injury woes have worsened with the news that star striker Robert Lewandowski has suffered a muscle tear in his left thigh and will be out of action for at least six weeks.