Liverpool slumped to an embarrassing 3-0 defeat at home against Nottingham Forest while Chelsea scored in each half for a 2-0 victory away at Burnley.
Chelsea's off-season reshuffle has thrust Marc Guiu into an unexpectedly prominent role, capping a turbulent few months for the young striker.
Chelsea will be without Cole Palmer for a crucial run of upcoming fixtures after the forward fractured his toe in a freak accident at home.
Chelsea have moved into the final stretch of November with renewed optimism as several key players edge closer to first-team action after a bruising period of injuries.
Estevao Willian has revealed how Enzo Maresca's calm guidance and "incredible" man-management have helped him settle quickly at Chelsea during his debut season in England.
Chelsea ended the weekend on a high with a 3-0 victory over Wolves, but the win was overshadowed by fresh injury concerns as Enzo Fernandez and Joao Pedro both requested substitutions late in the game.