Pep Guardiola has confirmed Rodri will not feature in FA Cup semi-final action against Southampton at Wembley on Saturday, with Manchester City opting for caution as the midfielder continues his recovery from a groin injury.
Rodri has been ruled out of Manchester City's trip to Burnley, dealing a significant setback to their Premier League title push.
Rodri has opened the door to a return to Spain, hinting at a possible move to Real Madrid as he nears the final year of his Manchester City contract.
Rodri is beginning to re-establish himself as a central figure for Manchester City after a long and uncertain road back from injury.
Pep Guardiola has admitted that Rodri returned from injury "too early" but insisted the Manchester City midfielder is steadily rediscovering his best form ahead of Saturday night's clash with Newcastle United.
Rodri has been charged with misconduct by the Football Association after criticising match officials following Manchester City's 2-2 draw with Tottenham earlier this month.