Ireland remain on course for a Six Nations Grand Slam but survived a huge scare against a much-improved Wales before completing a 27-18 victory at the Principality Stadium in Cardiff.
South African coach Franco Smith appears to have opened the door for the Wales coaching job after being linked to the role following Warren Gatland's departure.
Wales have announced the departure of head coach Warren Gatland with immediate effect after a run of 14 successive Test defeats.
Italy secured a 22-15 victory over Wales at the Stadio Olimpico, deepening Wales' Six Nations woes with a 14th consecutive defeat and all but confirming their second successive Wooden Spoon.
France flyhalf Romain Ntamack will find out his fate on Wednesday following the red card he received in the Six Nations opener against Wales.
The Springboks' victory over Wales and their end-of-year tour clean sweep means they will finish the year as the No 1 ranked side in the world.