Springbok hooker Bongi Mbonambi is an injury concern after he left the field during the Sharks' rout of the Bordeaux Begles on Saturday.
Sharks coach Joey Mongalo reflected on the 24-12 loss suffered at the hands of a spirited Connacht side in the URC on Saturday.
Following a demanding five-match schedule, the Sharks have opted to rest most of their stars for Saturday's URC clash with Connacht in Galway.
Lions head coach Ivan van Rooyen has handed former Sharks player Emile van Heerden his Lions debut against Munster in Cork on Friday.
Sharks talisman Siya Kolisi has confirmed he will join Racing 92 after the completion of the Rugby World Cup in France.
Sharks director of rugby Neil Powell admitted he was delighted with his team's 47-20 victory over the Bulls at Kings Park on Saturday, calling it an "important win".