Springbok coach Rassie Erasmus has used over 47 players so far in 2025, but his squad for the two home matches against Australia in the Rugby Championship will only be 36-strong.
Andy Farrell has named his son Owen Farrell to captain the team to face the First Nations and Pasifika XV in the final midweek fixture of the 2025 British and Irish Lions Tour of Australia.
Captain Harry Wilson leads an Australian team that features one debutant to face the British and Irish Lions in Brisbane on Saturday night.
South Africa continue to lead the World Rugby rankings, though New Zealand are narrowing the gap with only 1.06 points between the sides ahead of this weekend's fixtures.
Australia veteran James O'Connor is the surprise inclusion in Joe Schmidt's Wallabies squad to tackle the British and Irish Lions in the three-Test series.
Wallabies flyhalf Noah Lolesio has had surgery on an injury sustained against Fiji and will will miss the three-Test Series against the British and Irish Lions.