Bayer Leverkusen will host RB Leipzig in the standout tie of the German Cup last 16, while holders Bayern Munich have been handed a home meeting with second-division leaders Hertha Berlin.
Borussia Dortmund began their German Cup campaign in emphatic fashion on Tuesday, dispatching fifth-tier HEBC Hamburg 5-0 at the Volkspark Stadion.
Kylian Mbappe marked his last Paris Saint-Germain game by hoisting the Coupe de France, while Bayer Leverkusen claimed the German Cup.
RB Leipzig reached the German Cup semi-finals by beating Borussia Dortmund on Wednesday.