Arsenal will be without William Saliba and Gabriel Martinelli for Wednesday's Carabao Cup fourth-round clash against Brighton as Mikel Arteta's injury concerns continue to grow.
Saturday's Premier League action saw Manchester United continue their good form as both Chelsea and Liverpool suffered damaging defeats.
Newcastle United boss Eddie Howe has admitted his side's midfield "didn't function well" during their 2-1 defeat to Brighton at the Amex Stadium.
Chelsea's injury crisis deepened on Saturday as the Blues fell 3-1 at home to Brighton, with Trevoh Chalobah's red card adding to an already stretched squad.
Chelsea head coach Enzo Maresca admitted his frustration after a costly red card helped turn a dominant performance into a 3-1 home defeat against Brighton on Saturday.
Tottenham manager Thomas Frank praised his team's mentality and resilience after they came from 2-0 down to draw 2-2 at Brighton - a result he believes marks their best performance of the season.