Abafana Bes’thende will host Stellenbosch FC at the King Zwelithini Stadium in the Nedbank Cup Round of 16 on Saturday evening, with kick-off scheduled for 18:00.
With experienced coach Gavin Hunt now in charge and several additions made during the January transfer window, Mngqithi believes Stellenbosch are a difficult side to assess as they continue to evolve under new leadership.
"It's not going to be an easy assignment, but we have to take it as it is because we are in it to fight until the end, and anything is possible in football," said Mngqithi
While some may suggest this is the ideal time to face a team adjusting to a new coach and fresh personnel, Mngqithi disagrees.
He says periods of transition can often heighten competition within the squad, as established players look to impress the new technical team while recent signings fight to secure regular starting roles.
He points to the arrival of players such as Tshegofatso Mabasa, Mosa Lebusa and Asekho Tiwani as examples of quality that can quickly change the dynamic of a team.
The two teams produced one of the most entertaining league encounters earlier this season, with Stellenbosch edging Arrows 4-3 in a thrilling seven-goal contest.
Heading into this Ke Yona Cup tie, Arrows will draw confidence from their recent defensive solidity, having scored five goals without reply in their last two matches, including a commanding 3-0 victory over Orbit College in the Round of 32.
Mngqithi emphasises his side must avoid unnecessary errors that could hand the opposition scoring opportunities.
The former Sundowns mentor also believes playing at home could provide a valuable boost for his players.
He says familiarity with the King Zwelithini Stadium surface and the backing of their supporters may offer a slight advantage.
"I am hapy that the draw allowed us to play at home because we are familiar with the dimensions and quality of the pitch, and we can only hope that we will be able to perform on the day."