Attack coach Patrick Arlettaz says France's desire to beat the Springboks remains as strong as ever, while Paul Willemse admitted Les Blues are out for revenge.
Springbok prop Ox Nche sustained a season-ending injury in the Boks' 61-7 victory over Japan on Saturday.
Two late tries from the All Blacks helped them secure a 26-13 win over Ireland at a sold-out Soldier Field in Chicago on Saturday night.
Rassie Erasmus lauded his team for their physicality, intensity, and the respect they showed Japan as they registered an emphatic 61-7 victory at Wembley Stadium in London on Saturday.
Hooker Codie Taylor is eager to make amends for the All Blacks' loss to Ireland in Chicago in 2016 this weekend.
Injuries sustained in the Top 14 have forced France boss Fabien Galthie to make two changes to his squad for the three-match November campaign that starts against the Springboks on November 8.