Wallabies loose forward Rob Valetini will miss the first Bledisloe Cup clash against the All Blacks at Eden Park on Saturday.
Springbok fullback Aphelele Fassi is likely to miss the rest of the international season after having surgery on his ankle this week.
Wallabies flyhalf James O'Connor is available for selection for the first Bledisloe Cup Test in Auckland on Saturday, 27 September.
Just over seven weeks after initially retiring, veteran Wallabies scrumhalf Nic White has confirmed his retirement from international rugby once again.
Springbok coach Rassie Erasmus revealed there are three injured players who have been released from the Rugby Championship squad that will face Argentina.
Argentina have been handed a significant boost ahead of their Rugby Championship clash with the Springboks in Durban.