The Stormers and Bulls will kick off the 2025/26 United Rugby Championship season at home against Leinster and Ospreys, while the Sharks and Lions start their campaigns in Glasgow and Cardiff in the final weekend of September.
Springbok forward Ruan Venter returns to the Lions starting XV as one of two changes made by coach Ivan van Rooyen ahead of their United Rugby Championship clash with Scarlets at Ellis Park on Sunday.
Lions loose forward Ruhan Straeuli has been forced into early retirement at the age of 26 due to a serious neck injury that required surgical intervention in March.
The Bulls, Lions, Sharks and Stormers have been assured of their participation in the United Rugby Championship for the next four years.
The Lions snapped a five-match winless streak after beating Connacht 26-7 in their United Rugby Championship clash at Ellis Park on Saturday.
Saturday's Round 16 of the United Rugby Championship clash sees the Lions up against Irish outfit Connacht at Emirates Airline Park.