England ended their long wait for a victory over a Tier 1 nation with a gutsy 26-25 win over France at Allianz Stadium on Saturday.
Ireland began their quest for a third successive Six Nations title in dominant fashion, securing a 27-22 bonus-point victory over England in Dublin.
England head coach Steve Borthwick has suggested that Ireland stray beyond the line of legality at the breakdown and hopes that it is picked up by this weekend's referee.
England ended their five-game losing run with a nine-try defeat of Eddie Jones Japan at Twickenham on Sunday.
The Springboks made it two wins from two on their end-of-year tour as they defeated a spirited England side 29-20 in front of a sold-out Twickenham.
Heading into this crunch Castle Outgoing Tour test match against England at Twickenham later today, Springboks head coach Rassie Erasmus has spoken about their not-so-proud record against the hosts at their home venue, especially in the last four years.