The clash at the headquarters of SA Boxing pits blood against blood and marks a significant moment for one of the country’s most storied boxing dynasties.
Speaking on the birthday of his dad, the late, great Andre Thysse, Bryan says this fight is strictly business.
"Sparring is sparring, but on fight night, it's something different. Mentally, I think me and Coach Damian spoke at the beginning when we got the contract, and we just prepared ourselves," said Bryan.
"It's not me fighting a family member, it's me fighting someone that's in my way to becomming great, and unfortunately that's business, it's the way it is."
Bryan Thysse defeated Michael Head in October to capture the once vacant SA title, and did so with technical brutality, but his trainer Damien Durandt anticipates a tough contest against an opponent he shared countless years and sparring sessions with.
The trainer of both Bryan and Brandon Thysse, Durandt believes a historic night lies in store for fight fans on Saturday.
"I'm glad they got their belt and they can show their family, and it can be alongside their father's SA belt, and its extra special," he added.
"I'm glad to be part of this history that these two boys have made, and I'm looking forward to Saturday night."
The announcement of the fight surprised many people in the boxing community at first, but an all-Thysse tussle might just make for a fight of the year contender.
Damien Durandt will be in the corners of two South African Champions and brothers on Saturday night, proving once again the continuation of Andre Thysse’s legacy as Bryan prepares to defend his title for the very first time.
The well-respected trainer says it’s time to put family aside…
Boxing fans are sure to be royally entertained on Saturday night when Bryan and Gerhard Thysse must settle a family feud before Brandon Thysse and Roarke Knapp clash for the third time in the main event.