Veteran Proteas wicket-keeper Quinton de Kock has reversed his One Day International retirement after two years, and has been included in both the ODI and T20I squads to face Pakistan and Namibia.
Proteas captain Temba Bavuma has been ruled out of next month's two-match Test series in Pakistan due to a calf strain with Aiden Markram set to lead the red-ball team.
The deciding third T20 between England and South Africa was called off without a single delivery being bowled due to persistent rain.
Proteas head coach Shukri Conrad said his bowlers were "bereft of ideas" after conceding a record total of more than 300 against England in the second T20I at Old Trafford on Friday.
Phil Salt led a ruthless England batting display as they thrashed South Africa by 146 runs in the second T20I on Friday — the home side's biggest win in the format and the Proteas' heaviest defeat.
Two South African cricket stalwarts have been added to a worrying Proteas' injury list.