Ireland are set to "host" the Proteas for two T20Is and three ODIs in Abu Dhabi in late September and October.
Nandre Burger and Tony de Zorzi have earned their first Proteas national contracts while the most notable omission from the 18-man list is fast bowler Anrich Nortje.
Proteas fast bowler Lungi Ngidi has been ruled out of the upcoming Indian Premier League (IPL) season with Delhi Capitals due to a lower back injury.
English county side Yorkshire have signed Proteas wicketkeeper-batter Donovan Ferreira for this year's domestic T20 Blast competition.
Proteas batter Tristan Stubbs entered the record books when he smashed a triple century for the Warriors in a South African domestic first-class match against the Tuskers in Pietermaritzburg.
Mike Procter, the first man to coach the Proteas after South Africa's post-Apartheid return to international cricket, has passed away.