Midfielder Christian Eriksen is expected to have a scan on his ankle after leaving Old Trafford on crutches following Saturday’s 3-1 FA Cup victory over Reading.
Tottenham Hotspur assistant coach Cristian Stellini played down an injury concern for Richarlison after the Brazilian missed Saturday’s 3-0 FA Cup win at Preston.
Son Heung-min led the charge for Tottenham, in Harry Kane's absence, to help Spurs into the fifth round of the FA Cup with a 3-0 win over Preston.
Nathan Ake proved the unlikely match-winner as Manchester City edged out title rivals Arsenal 1-0 in a tense FA Cup fourth-round tie on Friday.
Leeds' club-record signing Georginio Rutter could make his debut against Accrington in the FA Cup on Saturday.
Tottenham manager Antonio Conte is determined to be the man who ends the club's trophy drought, according to Spurs' FA Cup-winning skipper Gary Mabbutt.