Wallabies centre Len Ikitau has been ruled out for a significant portion of the season after sustaining a shoulder injury that will require surgery.
Australia captain Harry Wilson is keen to face New Zealand in the 2027 Rugby World Cup opening match.
Italy stunned Australia in Udine, the All Blacks needed a late try to overcome Scotland while Ireland and England recorded wins in the Autumn Nations Series on Saturday.
England scored four tries to beat Australia 25-7 at the Allianz Stadium, Twickenham on Saturday.
The Wallabies welcome back key personnel for their Test against England in London on Saturday.
Aidan Ross and Kalani Thomas are the two potential debutants in the Wallabies' 34-player squad for the upcoming End of Year Tour.