Springbok Jordan Hendrikse will start at flyhalf for the Sharks when they face the Bulls in their United Rugby Championship clash in Durban on Saturday.
The Bulls squandered a commanding position as they fell 46-33 to defending champions Bordeaux Begles in their Champions Cup opener at Loftus.
Springbok loose forward Elrigh Louw will make his long-awaited return from injury when the Bulls face the Lions at Loftus Versfeld on Saturday.
Days after securing Springbok duo Jan-Hendrik Wessels and Cameron Hanekom on extended deals, the Bulls have once again flexed their muscles by confirming a host of new long-term contracts.
The Glasgow Warriors extended their impressive home record in the United Rugby Championship with a gritty 21-12 victory over the Bulls at Scotstoun Stadium on Friday night.
The Bulls have made eight positional changes to their line-up for Friday's United Rugby Championship fixture against Glasgow Warriors in Scotland.