The Cheetahs will be looking to avenge their painful semi-final loss to the Pumas in last year's Currie Cup when the two teams meet on Saturday to decide the destination of the trophy.
The Sharks suffered a disappointing exit from the Currie Cup semi-finals, losing 26-20 to the defending champions the Pumas at Kings Park.
The Lions got the better of the Griffons, while the Pumas saw off Griquas in Friday's Currie Cup action.
Sharks' Ntuthuko Mchunu scored two tries in the second half, leading his team to a 29-21 victory over the Lions and securing a home semifinal in the Currie Cup.
There were wins for the Sharks and Western Province on Friday as the Currie Cup season continued its march towards an exciting climax next month.
The Sharks scored two tries in the final five minutes to snatch a dramatic 24-22 victory over the Pumas in their Currie Cup game played in Nelspruit on Friday.