In a statement given to Sky Sports, Raducanu's team revealed: "After latest consultation with her team, Emma will have to miss the US Open.
"While she is working hard to rehab her stress fracture, given the nature of the injury, it needs time to heal. She is sad to be missing a tournament that is so special to her."
It's another major blow for Raducanu, who has missed most of the 2026 season at this point.
The star didn't play a single event on the clay court swing and her run to the Queen's final was her only grass court tournament before injury struck again.
Speaking on Sky Sports Tennis, Annabel Croft said: "It feels as if she's been unbelievably unluck with the injury problems she's faced throughout the course of her career. Don't forget she's had wrist surgery, feet problems, and now this stress fracture.
"And, you know there are so many injuries out there on the Tour, it seems like she never gets a clear run where she's able to really go for it with her tennis, and her body, and her mind injury free. And just keep the momentum going because we're all so excited with what she did at Queen's Club, where she reached the final there just ahead of Wimbledon, where everyone is going 'Wow'.
"She really ignited her tennis again and thing were really starting to look up, but this is just a major setback. It's a tournament that is so special to her, that's where she's had her greatest success, a former US Open champion, and I've seen lots of pictures of her posting the boot on her leg, trying to serve still, keeping her racket going.
"Showing everybody that she's doing everything she can, but clearly it's not healed up and you need to be fully fit to play these tournaments."