The typically intense Yorkshire-Lancashire derby saw plenty of physical challenges, even if clear-cut chances were limited outside of the two goals.
Manchester United took the lead in the 35th minute through a well-worked move when Amad Diallo found Youri Tielemans overlapping on the right; the Belgian's low cross was met perfectly by Bryan Mbeumo at the near post, who guided it past James Trafford.
Leeds responded strongly after the break, and just six minutes into the second half, Tarik Muharemovic headed a right-sided corner down to Dominic Calvert-Lewin, who controlled the ball and smashed a right-footed finish past Senne Lammens to level at 1-1.
Leeds dominated possession with around 63 per cent of the ball throughout the match and looked the more likely team to take all three points in the second half, but ultimately could not find a winner.
Manchester United were dangerous on the counter but will be fairly disappointed they couldn't control the match more.
The result keeps Leeds' solid start to the 2026-27 season going, as they remain unbeaten at home.
Meanwhile, the draw extends a difficult run of form for Manchester United, who have picked up just four points from their last seven matches, leaving them in the lower half of the table.
Pressure on Michael Carrick continues to mount after a midweek setback in the Champions League.